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Category: Aromatics, Heterocycles, Inhibitors, Isotope Labelled Compounds, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: Whiteto Off-White Solid /// Application Notes: Apixaban-d3 is labelled Apixaban (A726700) which is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation. /// References: Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011)| Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011)| barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011)|