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Category: Amines, Aromatics, Metabolites and Impurities /// Appearance: Light Brown Solid /// Application Notes: 2-Amino-3-methylbenzoic acid is a metabolite of Lidocaine (L397800), an antiarrythmic drug that is used to treat patients with ventricular fibrillation. 2-Amino-3-methylbenzoic acid has potential herbicidal activity, and is also used as a reagent to synthesize Ropicavaine (R675000), a local anasthetic. /// References: Dorian, P., et al.: New Eng. J. Med., 346, 884 (2002)| Emanuelsson, B., et al.: Eur. J. Pharm. Sci., 5, 171 (1997)| Kammerer, R. & Schmitz, D.: Xenobiotica, 16, 681 (1986)| McClure, J.: Brit. J. Anasth., 76, 300 (1996)| Thomas, G.: J. Agr. Food Chem., 32, 747 (1984)