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Beschreibung

Category: Inhibitors, Protein Kinase Inhibitors and Activators /// Appearance: White to Off-White Solid /// Application Notes: W7 is a vascular relaxing agent which affects vascular smooth muscle actomyosin. W7, an inhibitor of actomyosin superprecipitation, produces relaxation of isolated rabbit arterial strips and antagonizes the contraction of the strips induced by various contractile agonists. W7 is also a calmodulin antagonist that binds to calmodulin and inhibits Ca2+/calmodulin-regulated enzyme activities. /// References: Hidaka, H., et al.: Proc. Nat. Acad. Sci. USA, 78, 4354 (1981)