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Beschreibung

Category: Metabolites and Impurities, Pharmaceuticals, Intermediates and Fine Chemicals, Sulfur and Selenium Compounds /// Appearance: White to Off-White Solid /// Application Notes: Amifostine Thiol is a metabolite of Amifostine (A576810) which provides normal cells with selective protection against the toxic effects of cancer chemotherapy and radiation treatment. /// References: Satge, J., et al.: Eur. J. Med. Chem., 24, 48 (1989)| Geary, R.S., et al.: Biopharm. Drug Dispos., 12, 261 (1991)| Brown, D.Q., et al. Pharmacol. Ther., 39, 159 (1988)| Capizzi, R.L., et al.: Cancer, 72, 3495 (1993)| Treskes, M., et al.: Cancer Chemother. Pharmacol., 33, 93 (1993)