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Category: Aromatics, Inhibitors, Pharmaceuticals, Intermediates and Fine Chemicals /// Application Notes: Alizarin is used widely as a prominent red dye for textile facbrics. Alizarin red is now used in biochemical assay to determine quantitatively by colorimetry, the presence of calcific deposition by cells of the osteogenic lineage. Alzarine derivatives was evaluated as new inhibitors of the HIV-1 reverse transcriptase associated DNA polymerase and RNase H. Alizarin was also shown to inhibit proliferation, tumor growth and suppress tumorigenesis in human osteosarcoma and breast cancer cell representative for bone metastasis. /// References: Yuan, H.S., et al.: Mycol., 3, 100 (2012)| Esposito, F. et al.: FEBS. J., 278, 1444 (2011)| Fotia, Caterina, J. Orthop. Rsch. 30, 1486 (2012)|