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Beschreibung

A cell-permeable dipeptide that acts as a selective and reversible PPARgamma antagonist (KD ~8 µ,M). Shown to inhibit the agonist activity of Rosiglitazone (100 nM) in a dose-dependent manner (IC50 = 31.9 µ,M) in transfected COS-7 cells., A cell-permeable dipeptide that acts as a selective and reversible PPARgamma antagonist (KD = ~ 8 µ,M). Shown to inhibit the agonist activity of Rosiglitazone (100 nM) in a dose-dependent manner (IC50 = 31.9 µ,M) in transfected COS-7 cells.