Artikelnr.
SAF-5058750001
CAS-Nummer
[485-49-4]
Einheit
EA
Molekularformel
C20H17NO6
Molekulargewicht
367,36
Transportdaten
UN1544 (6.1) II E4
A potent allosteric antagonist of vertebrate GABAA receptors. Blocks GABAA-induced chloride currents in cultured neurons (IC50 = 740 nM). Shown to increase blood pressure in spontaneously hypertensive rats and cause convulsion in experimental animals. Also, increases the amplitude of spontaneous colonic contractions.
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