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Beschreibung

"Native coagulation factor V from human plasma. Thrombin cleaves Factor V to yield activated Factor Va, which exhibits 50-fold greater activity than the precursor molecule. Factor Va, Ca2+, and membrane phospholipids are cofactors which form a ""prothrombinase"" complex with Factor Xa, enabling its proteolytic activation of prothrombin to thrombin., Native coagulation factor V from human plasma. Thrombin cleaves Factor V to yield activated Factor Va, which exhibits 50-fold greater activity than the precursor molecule. Factor Va, Ca2+, and membrane phospholipids are cofactors that form a ""prothrombinase"" complex with Factor X, enabling its proteolytic activation of prothrombin to thrombin."