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Beschreibung

N-terminal GST-tagged, recombinant, human, full-length p38alpha/SAPK2a containing the mutation T106M. Activated using DD-MKK6 (14-537) and repurified using glutathione- agarose. Contains the gatekeeper mutation T160M in the ATP-binding domain. This mutation increases resistance to SB203580 as compared to the wild type sequence. , Product Source: Human, full-length p38alpha/SAPK2a containing the mutation T106M. Expressed in E. coli.