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Description
Category: Chiral Reagents, Inhibitors, Mutagenesis Research Chemicals, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: White to Off-White Solid /// Application Notes: Deoxynivalenol is a tricothecene mycotoxin and potent protein synthesis inhibitor. Deoxynivalenol exhibits cytotoxic activity in vivo via the ribotoxic stress response. Deoxynivalenol induces p38-mediated gene expression and apoptosis in leukocytes, activity results in systemic expression of interleukin-6 (IL-6) and other proinflammatory cytokines. Also induces migration of NF-?B into the nucleus.Environmental contaminants, Food contaminants /// References: Bae, et al.: Toxicol. Sci., 105, 59 (2008), Shi, et al.: Toxicol. Sci., 109, 247 (2009), Krishnaswamy, et al.: Free Radic. Biol. Med., 49 50 (2010)
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Quality analytical standards and reference materials for food and environmental analysis, research
Founded in 1982, Toronto Research Chemicals is specialized in the development and production of reference materials used in research as well as food safety testing and environmental analysis. The range of more than 350,000 products includes reference standards for pesticides and metabolites, impurities, natural compounds and complex organic small molecules not otherwise commercially available.