2-[(3-Nitrophenyl)methylene]-3-oxo-butanoic Acid 2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimethylethyl Ester Hydrochloride - TRC-N504405-10MG

Description

Appearance: Yellow Solid /// Application Notes: 2-[(3-Nitrophenyl)methylene]-3-oxo-butanoic Acid 2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimethylethyl Ester Hydrochloride is an intermediate in synthesizing 5-Ethyl-demethyl Lercanidipine (E913200), which is an impurity of Lercanidipine (L179000), a dihydropyridine calcium channel blocker. /// References: Bianchi, G., et al.: Pharmacol. Res., 21, 193 (1989)| Rimoldi, E., et al.: Acta Therap., 200, 23 (1994)| Argekar, A., et al.: J. Pharm. Biomed. Anal., 21, 1137 (2000)|

Structure formula

2-[(3-Nitrophenyl)methylene]-3-oxo-butanoic Acid 2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimethylethyl Ester Hydrochloride

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Method

2-[(3-Nitrophenyl)methylene]-3-oxo-butanoic Acid 2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimethylethyl Ester Hydrochloride

[929212-20-4]

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