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Beschreibung

Category: Amines, Chiral Reagents, Impurities, Isotope Labelled Compounds, Pharmaceuticals, Intermediates and Fine Chemicals /// Application Notes: Aliskiren-d6 N-Maleic Acid (Mixture of Diastereomers) is the labeled analogue of Aliskiren N-Maleic Acid (Mixture of Diastereomers) (A536005), a degradation impurity of Aliskiren Hemifumarate (A536001), an orally active, synthetic nonpeptide renin inhibitor. Antihypertensive. /// References: Lefevre, G., et al.: J. Immunoassay, 21, 65 (2000)| Allikments, K., et al.: Curr. Opin. Invest. Drugs, 3, 1479 (2002)| Wood, J.M., et al.: Biochem. Biophys. Res. Commun., 308, 698 (2003)| Grandman, A.H., et al.: Circulation, 111, 1012 (2005)