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Beschreibung

Category: Amines, Heterocycles, Isotope Labelled Compounds, Metabolites and Impurities, Pharmaceuticals, Intermediates and Fine Chemicals, Steroids /// Application Notes: N-Des(1,1-dimethylethyl) N-Cyclohexyl Finasteride-d11 is the isotope labelled analog of N-Des(1,1-dimethylethyl) N-Cyclohexyl Finasteride (D289575), an impurity of Finasteride (F342000) which is an inhibitor of 5alpha-reductase, the enzyme that converts testosterone to the more potent androgen 5alpha-dihydrotestosterone.Also an antialopecia agent. /// References: Koronkowski, M.J., et al.: Pharmacotherapy, 13, 309 (1993)| Tenover, J.L., et al.: Clin. Ther., 19, 243 (1997)| McConnell, J.D., et al.: N. Engl. J. Med., 338, 557 (1998)